Human variability and susceptibility to trichloroethylene.
نویسندگان
چکیده
منابع مشابه
Human variability and susceptibility to trichloroethylene.
Although humans vary in their response to chemicals, comprehensive measures of susceptibility have generally not been incorporated into human risk assessment. The U.S. EPA dose-response-based risk assessments for cancer and the RfD/RfC (reference dose-reference concentration) approach for noncancer risk assessments are assumed to protect vulnerable human subgroups. However, these approaches gen...
متن کاملIdentification of trichloroethylene and its metabolites in human seminal fluid of workers exposed to trichloroethylene.
We have investigated the potential of the male reproductive tract to accumulate trichloroethylene (TCE) and its metabolites, including chloral, trichloroethanol (TCOH), trichloroacetic acid (TCA), and dichloroacetic acid (DCA). Human seminal fluid and urine samples from eight mechanics diagnosed with clinical infertility and exposed to TCE occupationally were analyzed. In in vivo experimental s...
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Climate variations influenced the agricultural productivity, health risk, and conflict level of preindustrial societies. Discrimination between environmental and anthropogenic impacts on past civilizations, however, remains difficult because of the paucity of high-resolution paleoclimatic evidence. We present tree ring-based reconstructions of central European summer precipitation and temperatu...
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متن کاملFatal addiction to trichloroethylene.
Trichloroethylene inhalation is a common industrial hazard that involves a risk of addiction. In the present case there was evidence of indulgence of addiction at work but not at home. The medical history suggested permanent paresis of the olfactory nerves in addition to intermittent gastric disturbance. Sudden death, not preceded by severe physical exertion, occurred some 17 hours after the la...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 2000
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.00108s2201